The Effects of Propofol and Sevoflurane Anaesthesia on Lipid Peroxidation and the Antioxidant System in Angora Goats

  • Ali Kumandas kırıkkale üniversitesi
  • Miyase Çınar Kirikkale University, Faculty of Veterinary Medicine, Department of Biochemistry. http://orcid.org/0000-0003-3806-9938
  • Mert Pekcan Department of Biochemistry, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
  • Ertuğrul Elma Kirikkale University, Faculty of Veterinary Medicine, Department of Surgery, Kirikkale
  • Birkan Karslı Department of Surgery, Faculty of Veterinary Medicine, Kirikkale University, Kirikkale, Turkey.
  • Zeynep Pekcan Department of Surgery, Faculty of Veterinary Medicine, Kirikkale University, Kirikkale, Turkey.
Keywords: Angora goat, Antioxidant status, Lipid peroxidation, Propofol, Sevoflurane

Abstract

The present study was aimed at the determination of the effects of propofol and sevoflurane administration on blood malondialdehyde levels and certain antioxidant parameters in goats. The study was conducted on 7 healthy Angora goats. Blood samples were taken from all of the animals prior to the administration of propofol, following the induction of anaesthesia, and 15, 30, 60 and 120 minutes and 24 hours after sevoflurane administration. The collected blood samples were used to measure plasma malondialdehyde (MDA), vitamin A and beta-carotene, vitamin E levels and erythrocyte superoxide dismutase (SOD) and catalase (CAT) activities. In the Angora goats, which were anaesthetized with propofol and sevoflurane, neither plasma MDA, vitamin A and β-carotene, vitamin E levels, nor erythrocyte SOD and CAT activities displayed any statistically significant difference during and after anaesthesia. In result, it was determined that propofol and sevoflurane anaesthesia did not induce any adverse effect on blood MDA levels or the antioxidant parameters investigated in the Angora goat.

Published
2019-09-19
Section
Articles